3D Ex Vivo Human Musculoskeletal System Tissue Model Introduction

What is Musculoskeletal System?

Defined as the most abundant tissue in the human body, this system is a dynamically complex tissue in which the three-dimensional (3D) organization of muscle fibers is ensured by a complex tubular network of extracellular matrix. The system consists of bones, cartilage, ligaments, tendons and connective tissue. This system has good regenerative properties and plays a vital role during exercise. However, a variety of factors can lead to pain and limitation of motion, such as aging, injury, and congenital anomalies. Developing 3D ex vivo models of human skeletal muscle may provide a promising tool for drug screening of related diseases.

Diagram of skeletal muscle structure.Fig.1 Diagram of skeletal muscle structure. (Scala, 2021)

Advantages of the Ex Vivo Model

Tissue ex vivo models generally describe a set of experiments performed on specific biological tissues alive in vitro, which provide insight into the function and behavior of complex biological systems. There are many advantages to such models.

Fig.2 Advantages of the model. (Creative Biolabs)Fig.2 Advantages of the model. (Creative Biolabs)

3D Ex Vivo Human Musculoskeletal System Tissue Model at Creative Biolabs

Ex vivo models of skeletal muscle, including myofibers as well as intact muscle, have enabled some seminal discoveries in the field of muscle physiology. They provide a powerful platform for studying key muscle structure-function relationships. There are many kinds of ex vivo models of skeletal muscle, which play a vital role in many fields.

3D Ex Vivo Human Bone Tissue Model

Such models are closely related to several research areas, such as bone growth, bone metabolism, cancer cell-induced bone disease, bone repair and bone response to loading.

3D Ex Vivo Human Cartilage Tissue Model

This model is considered to be an efficient and economical system and a powerful tool for evaluating therapeutic approaches in preclinical studies of osteoarthritis treatment.

Features of Our 3D Ex Vivo Human Tissue Model

  • Ex vivo models of various tissues are available, including cartilage, bone, and tendon.
  • Histopathological confirmation by a professional team ensures you receive the most suitable specimen.
  • Standard and customized clinical data collections ensure corresponding donor history.
  • High-quality and customizable tissue models facilitate your research needs.
  • We are able to ethically collect diseased biospecimens as well as normal human biospecimens.
  • Our team of experts will customize a collection to your specific needs.

As an experienced supplier of isolated tissue models, Creative Biolabs is confident in providing customized solutions for musculoskeletal research. Our diverse ex vivo models ensure optimal experimental results, which can help facilitate preclinical drug development. Please contact us in time for more details.

Reference

  1. Scala, P.; et al. Stem cell and macrophage roles in skeletal muscle regenerative medicine. International Journal of Molecular Sciences. 2021, 22 (19): 10867.
Research Model

Related Sections:

USA
UK
Germany
Inquiry Basket
Copyright © Creative Biolabs. All Rights Reserved.
Top