This product is a Raji-Luc2 B cell engineering tool based on the Nanoparticles (Fucoidan/P-selectin) delivery system and CRISPR-based (hROSA26-sgRNA-Cpf1-SCR7 pyrazine ) genome editor.
| Host Cell | Raji-Luc2 |
| Target | BCMA |
| Insert Clone | 171 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Fucoidan/P-selectin |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | 10-1000 |
| Charge (mv) | <-25 |
| Total Atom Count | ~20,000,000 |
| Surface Atoms (%) | ~4 |
| Specific Surface Area (m2/g) | ~8 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Colon cancer |
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