BCMA mAb (8B4) Farage B Cell Engineering Cassette (CAT#: BGS-0124-CR2739)

This product is a Farage B cell engineering tool based on the Gold nanoparticles (EpCAM aptamer/Epithelial celladhesion molecule) delivery system and CRISPR-based (CCR5-sgRNA-Cpf1-Brefeldin A ) genome editor.

Datasheet

Specifications

Host Cell Farage
Target BCMA
Insert Clone 8B4
Safe Harbor Sites (SHS) CCR5
gRNA sgRNA
Nuclease Cpf1
Enhancer Brefeldin A
Targeting Strategy pH responsive, time-dependent
Insertion sites Large DNA sequences
Vehicles Gold nanoparticles
Ligand/Receptor EpCAM aptamer/Epithelial cell
adhesion molecule
Active Agents Celastrol
Particle Size <2500
Charge (mv) −10 to -50
Total Atom Count ~65,000,000
Surface Atoms (%) ~0.6
Specific Surface Area (m2/g) ~0.8
Vector Type Adenoviruses
Vector Name BCpCDH3
Targeting Diseases Ovarian cancer; Breast cancer; Colon cancer
COA

Certificate of Analysis Lookup

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! For Research Use Only | Not For Clinical Use

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