This product is a ST486 B cell engineering tool based on the Nanoparticles (Tumor-homing peptide tLyp-1/NRP-1) delivery system and CRISPR-based (CCR5-tracr RNA-SpCas9-RS-1) genome editor.
| Host Cell | ST486 |
| Target | CCL2 |
| Insert Clone | BG-56E |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | tracr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Mouse genome E-1 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Tumor-homing peptide tLyp-1/NRP-1 |
| Active Agents | Paclitaxel, chlorin e6 |
| Particle Size | ≤10000 |
| Charge (mv) | -15 to -310 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.