This product is a Ramos (RA 1) B cell engineering tool based on the Niosomes (Fucoidan/P-selectin) delivery system and CRISPR-based (huROSA-26-sgRNA-Cpf1-L755507) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | CCL2 |
| Insert Clone | BG-57E |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Niosomes |
| Ligand/Receptor | Fucoidan/P-selectin |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | <500 |
| Charge (mv) | -31 to -200 |
| Total Atom Count | -22,000,000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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