This product is a GA-10 (Clone 4) B cell engineering tool based on the Magnetic nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-Nocodazole) genome editor.
| Host Cell | GA-10 (Clone 4) |
| Target | CCL2 |
| Insert Clone | BG-65E |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Regorafenib |
| Particle Size | 1-100 |
| Charge (mv) | 15-60 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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