This product is a Pfeiffer B cell engineering tool based on the Nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-317-huIgH296-Cas9-L755507) genome editor.
| Host Cell | Pfeiffer |
| Target | CCL2 |
| Insert Clone | BG-71E |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | huIgH296 |
| Nuclease | Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Bortezomib |
| Particle Size | 10-50 |
| Charge (mv) | ≤50 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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