This product is a BC-3 B cell engineering tool based on the Niosomes (EGFR mAb/Epidermal Growth Factor Receptor) delivery system and CRISPR-based (SHS-317-tracr RNA-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | BC-3 |
| Target | DENV |
| Insert Clone | TCam2I |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Niosomes |
| Ligand/Receptor | EGFR mAb/Epidermal Growth Factor Receptor |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | 41-3500 |
| Charge (mv) | −27 to -47 |
| Total Atom Count | -61000000 |
| Surface Atoms (%) | -0.7 |
| Specific Surface Area (m2/g) | -3.6 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Brain cancer; Colon cancer; Ovarian cancer |
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