This product is a BC-3 B cell engineering tool based on the Gold nanoparticles (EGFR mAb/Epidermal Growth Factor Receptor) delivery system and CRISPR-based (hROSA26-tracr RNA-Cas9-Brefeldin A) genome editor.
| Host Cell | BC-3 |
| Target | DENV |
| Insert Clone | HMB-DV4C |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | EGFR mAb/Epidermal Growth Factor Receptor |
| Active Agents | Thymoquinone |
| Particle Size | <3450 |
| Charge (mv) | 3 to 21 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Breast cancer; Lung cancer; Brain cancer; Colon cancer; Ovarian cancer |
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