This product is a Ramos (RA 1) B cell engineering tool based on the Gold nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-321-tracr RNA-SpCas9-L755507) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | EPHA1 |
| Insert Clone | BCGR-0960CR |
| Safe Harbor Sites (SHS) | SHS-321 |
| gRNA | tracr RNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | <500 |
| Charge (mv) | <-1 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Breast cancer; Lung cancer; Ovarian cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.