This product is a Raji B cell engineering tool based on the Dendrimers (Mannose/Mannose receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-Brefeldin A) genome editor.
| Host Cell | Raji |
| Target | EphA2 |
| Insert Clone | 2A4CR |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-3 |
| Vehicles | Dendrimers |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | ≤900 |
| Charge (mv) | -25 to -125 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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