This product is a Raji-Luc2 B cell engineering tool based on the Solid lipid nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (AAVS1-sgRNA-Cpf1-Nocodazole) genome editor.
| Host Cell | Raji-Luc2 |
| Target | EphA2 |
| Insert Clone | B6CR62 |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Regorafenib |
| Particle Size | 20-2850 |
| Charge (mv) | -15 to -185 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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