This product is a Ramos (RA 1) B cell engineering tool based on the Nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-227-tracr RNA-Cas9-Nocodazole) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | EphA2 |
| Insert Clone | D2-1B1CR |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Thymoquinone |
| Particle Size | 20-2850 |
| Charge (mv) | 10 to 100 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Baculovirus-AAV |
| Vector Name | BCpCDH4 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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