This product is a BC-2 B cell engineering tool based on the Microbubbles (Mannose/Mannose receptor) delivery system and CRISPR-based (hROSA26-sgRNA-Cpf1-L755507) genome editor.
| Host Cell | BC-2 |
| Target | EphA2 |
| Insert Clone | A3D10CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Mouse genome E-2 |
| Vehicles | Microbubbles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | 10-500 |
| Charge (mv) | 17 to 58 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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