This product is a NCI-H929 [H929] B cell engineering tool based on the Liposomes (Folate/ Folate Receptor) delivery system and CRISPR-based (hROSA26-sgRNA-Cpf1-L755507) genome editor.
| Host Cell | NCI-H929 [H929] |
| Target | ETFB |
| Insert Clone | BCGR-1327CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Large DNA sequences |
| Vehicles | Liposomes |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | ≤900 |
| Charge (mv) | 0 to -16 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Prostate cancer; Breast cancer; Pancreatic cancer; Thyroid carcinoma; Melanoma; Colorectal cancer |
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