This product is a Raji-Luc2 B cell engineering tool based on the Nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | FANCE |
| Insert Clone | BCG-1724CR |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | Bortezomib |
| Particle Size | 20-2850 |
| Charge (mv) | 10 to 55 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer |
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