This product is a MC/CAR B cell engineering tool based on the Solid lipid nanoparticles (Hyaluronic acid/ RHAMM, CD44) delivery system and CRISPR-based (hROSA26-crispr RNA-SpCas9-L755507) genome editor.
| Host Cell | MC/CAR |
| Target | FANCE |
| Insert Clone | BCG-2841CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Hyaluronic acid/ RHAMM, CD44 |
| Active Agents | Thymoquinone |
| Particle Size | <1660 |
| Charge (mv) | 13 to 65 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer |
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