FANCE mAb (L5-P1E6/G5CR) Raji B Cell Engineering Cassette (CAT#: BGS-0424-CR604)

This product is a Raji B cell engineering tool based on the Gold nanoparticles (EpCAM aptamer/Epithelial cell adhesion molecule) delivery system and CRISPR-based (AAVS1-sgRNA-Cas9-RS-1) genome editor.

Datasheet

Specifications

Host Cell Raji
Target FANCE
Insert Clone L5-P1E6/G5CR
Safe Harbor Sites (SHS) AAVS1
gRNA sgRNA
Nuclease Cas9
Enhancer RS-1 (RAD51-stimulatory compound 1)
Targeting Strategy pH responsive, time-dependent
Insertion sites Human genome
Vehicles Gold nanoparticles
Ligand/Receptor EpCAM aptamer/Epithelial cell adhesion molecule
Active Agents Talazoparib, temozolomide
Particle Size 1-100
Charge (mv) <-25
Total Atom Count -75000000
Surface Atoms (%) -0.65
Specific Surface Area (m2/g) -0.7
Vector Type Adenoviruses
Vector Name BCpCDH3
Targeting Diseases Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer
COA

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! For Research Use Only | Not For Clinical Use

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