This product is a Raji B cell engineering tool based on the Solid lipid nanoparticles (Tumor-homing peptide tLyp-1/NRP-1) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-RS-1) genome editor.
| Host Cell | Raji |
| Target | FAP |
| Insert Clone | BCG-0295CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Human genome |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Tumor-homing peptide tLyp-1/NRP-1 |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | 10-500 |
| Charge (mv) | 17 to 58 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | Baculovirus-AAV |
| Vector Name | BCpCDH4 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Colon cancer |
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