This product is a GA-10 (Clone 4) B cell engineering tool based on the Dendrimers (EGFR mAb/Epidermal Growth Factor Receptor) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-RS-1) genome editor.
| Host Cell | GA-10 (Clone 4) |
| Target | FEN1 |
| Insert Clone | BCG-2399CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Large DNA sequences |
| Vehicles | Dendrimers |
| Ligand/Receptor | EGFR mAb/Epidermal Growth Factor Receptor |
| Active Agents | Bortezomib |
| Particle Size | 10-50 |
| Charge (mv) | 10 to 35 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Colorectal cancer; Lung cancer |
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