This product is a Raji-Luc B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-317-huIgH296-SpCas9-RS-1) genome editor.
| Host Cell | Raji-Luc |
| Target | FEN1 |
| Insert Clone | BCG-1192CR |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | huIgH296 |
| Nuclease | SpCas9 |
| Enhancer | RS-1 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | DOX |
| Particle Size | <100 |
| Charge (mv) | <-1 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Breast cancer; Colorectal cancer; Lung cancer |
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