This product is a NCI-H929 [H929] B cell engineering tool based on the Liposomes (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-229-tracr RNA-Cas9-RS-1) genome editor.
| Host Cell | NCI-H929 [H929] |
| Target | FOLH1 |
| Insert Clone | BG-19F |
| Safe Harbor Sites (SHS) | SHS-229 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Liposomes |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Regorafenib |
| Particle Size | ≤10000 |
| Charge (mv) | ≤50 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer; Ovarian cancer; Liver cancer |
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