This product is a SU-DHL-10 B cell engineering tool based on the Quantum dots (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-227-crispr RNA-SpCas9-SCR7 pyrazine) genome editor.
| Host Cell | SU-DHL-10 |
| Target | FOLH1 |
| Insert Clone | BG-18F |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-2 |
| Vehicles | Quantum dots |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | 1-100 |
| Charge (mv) | 8-55 |
| Total Atom Count | -64,000,000 |
| Surface Atoms (%) | -0.5 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer; Ovarian cancer; Liver cancer |
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