This product is a Farage-Luc2 B cell engineering tool based on the Gold nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-255-SpCas9-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Farage-Luc2 |
| Target | KIR3DL2 |
| Insert Clone | 71LTH71L |
| Safe Harbor Sites (SHS) | SHS-255 |
| gRNA | SpCas9 |
| Nuclease | Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Mouse genome E-5 |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | DOX |
| Particle Size | ≤24100 |
| Charge (mv) | 17-61 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Breast cancer; Lung cancer |
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