This product is a SU-DHL-5 B cell engineering tool based on the Nanoparticles (Anisamide/ Sigma receptors) delivery system and CRISPR-based (CCR5-SpCas9-NLS-Cas9-RS-1) genome editor.
| Host Cell | SU-DHL-5 |
| Target | MIF |
| Insert Clone | MORQ71L4CQ9T |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Anisamide/ Sigma receptors |
| Active Agents | Thymoquinone |
| Particle Size | <3450 |
| Charge (mv) | ≤71 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer; Ovarian cancer; Liver cancer |
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