This product is a Raji B cell engineering tool based on the Magnetic nanoparticles (Tumor-homingpeptide tLyp-1/NRP-1) delivery system and CRISPR-based (CCR5-sgRNA-Cpf1-Brefeldin A) genome editor.
| Host Cell | Raji |
| Target | SSB |
| Insert Clone | B6CR519 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Mouse genomeD-4(2) |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | Tumor-homing peptide tLyp-1/NRP-1 |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | <500 |
| Charge (mv) | 0 to -30 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Colon cancer; Glioblastoma; Gastric cancer; Liver cancer |
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