Thomsen-Friedenreich mAb (BGC77) P3HR-1 B Cell Engineering Cassette (CAT#: BGS-0624-CR784)

This product is a P3HR-1 B cell engineering tool based on the Solid lipid nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (hROSA26-tracr RNA-SpCas9-L755507) genome editor.

Datasheet

Specifications

Host Cell P3HR-1
Target Thomsen-Friedenreich
Insert Clone BGC77
Safe Harbor Sites (SHS) hROSA26
gRNA tracr RNA
Nuclease SpCas9
Enhancer L755507
Targeting Strategy Enzyme responsive, time-dependent
Insertion sites Unproductive heavy chain
Vehicles Solid lipid nanoparticles
Ligand/Receptor MUC1 aptamer/MUC1
Active Agents AntimiR-21, doxorubicin (DOX)
Particle Size <241
Charge (mv) <81
Total Atom Count -23000000
Surface Atoms (%) -4
Specific Surface Area (m2/g) -7
Vector Type Lentivirus
Vector Name BCpCDH2
Targeting Diseases Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer
COA

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! For Research Use Only | Not For Clinical Use

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