Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Fab-scFv-Fc) (FABVC-130)

Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-CD7 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-saporin to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Datasheet INQUIRY

Specifications

Targets

CD7 & saporin

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Pretargeting system for immunotoxin delivery

Related Disease

Multiple myeloma (MM); Hematologic malignancies

Targets

Target 1

CD7

Gene ID

924

UniProt ID

P09564

Alternative Names

CD7 molecule; Cluster of differentiation 7; CD7; GP40; TP41; Tp40; LEU-9

Target 2

saporin

Alternative Names

Saporin; Ribosome inactivating protein; RIP

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD7 x Anti-saporin Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-130)

Specifications

Targets

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