Jak/Stat Phospho Antibody Array features 42 high-specificity antibodies targeting key nodes of the Jak/Stat signaling pathway, optimized for protein phosphorylation profiling in human, mouse, and rat cell and tissue samples. Each kit includes two identical array slides, enabling parallel analysis of two independent samples, such as a control specimen and a treated experimental sample.
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Product Property | |
|---|---|
| Species Reactivity | Human; Mouse; Rat |
| Sample Type | Cell lysate; Tissue lysate |
| Assay Type | Fluorescent Immunoassay |
| Detection Method | Fluorescence Scanning |
| Internal Controls | Beta-actin; GAPDH; Negative controls |
| Principle | Fluorescent immunoassay based on antibody microarray, for quantitative detection of Jak/Stat pathway phosphorylation levels. |
| Platform | Fluorescent Antibody Microarray |
| Specificity | Human |
| Cross-Reaction | Mouse; Rat |
| Product Content | 2 array slides per package for two samples (untreated vs. treated) |
| Slide Dimensions | 76 x 25 x 1 mm |
| Application Notes | ELISA based antibody array |
| Core Highlights | Site-specific phosphorylation profiling and screening with 42 antibodies Antibodies covalently immobilized on 3D polymer coated glass slide Fluorescent detection |
| Signaling Pathway | Jak/Stat Signaling Pathway |
| Storage | 2-8°C |
Target Information | |
|---|---|
| Analyte | Jak/Stat Pathway Phosphoproteins |
| Targets | JAK1 (Tyr1022), JAK2 (Tyr1007), JAK2 (Tyr221), MEK1 (Ser217), MEK1 (Ser221), MEK1 (Thr291), MEK2 (Thr394), p44/42 MAPK (Thr202), p44/42 MAPK (Tyr204), Raf1 (Ser259), Raf1 (Ser338), STAT1 (Ser727), STAT1 (Tyr701), STAT3 (Ser727), STAT3 (Tyr705), STAT4 (Tyr693), STAT5A (Ser780), STAT5A (Tyr694), STAT6 (Thr645), STAT6 (Tyr641), TYK2 (Tyr1054) |
| Target Source | Human; Mouse; Rat |
For Research Use Only.