Creative Biolabs offers chemical synthesis service to synthesize therapeutic compounds. Our company is able to synthesize nearly all compounds you required. We are able to offer a broad range of materials used in this process, including intermediates, reference compounds, starting materials, and derivatives. The scales of compounds range from milligrams to multi-gram, and we can offer purification service to improve the purity as well.
We have an innovative platform for chemical synthesis. Our specialized synthesis team has developed tools which open new possibilities to discover synthetic pathways, explore conditions, and optimize reaction parameters. Our synthesis reactor systems also can offer condition control, data management, and procedure optimization services which significantly reduced costs and overall producing time. Depending on your goal of the investigation and the output volume you required, our researchers will help you choose an appropriate version of synthesis reactor.
In the area of drug discovery and development, chemical synthesis has many applications.
Supplement the Supply of Natural-Source Drugs
Natural-source drugs tend to be small amounts and need complicated extraction and purification processes. Besides, if the demand for a natural resource material is great, this original material may face extinction. Chemical synthesis can be used to supply the natural-source drugs. Creative Biolabs uses chemical synthesis to make new compounds. We are able to synthesize new substances and involve chemical sequences and structure determination by various techniques.
Fighting Drug Resistance
Drug resistance has become a severe problem in recent years. Chemical modification strategy has been developed to make various analogs of existing drugs and provide new ways attacking drug-resistant pathogens. Creative Biolabs offers parallel synthesis service which prepares modules in separate and parallel reaction. The convergent-coupling reactions serve as branch points. During the synthesis step, a diverse range of structural modifications is allowed to be easily made.
Figure 1. A modular approach to macrolide synthesis (Yan and Baran 2016)
Structure-Based Drug Design
Apart from computer-based methods for structure-based drug design, Creative Biolabs also provides experimental-based high throughput screening methods with combinatorial chemistry, and parallel testing thousands of compounds for biochemical effects.
Protein Chemical Synthesis
Protein synthesis accomplished by reverse proteolysis offer a means of protein primary sequence modification and can be used for structure-function studies. De novo methods of synthesizing homogenous protein pharmaceuticals or target proteins can perform as a highly versatile tool for the study of protein structure and function. Creative Biolabs has state-of-the-art chemical protein synthesis technique and capable assembling proteins from individual amino acids.
Creative Biolabs performs chemical syntheses with the inexpensive, fast and high-quality output. For more detailed information, please feel free to contact us or directly sent us an inquiry.
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