Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsAs a pioneer and the undisputed global leader in the field of the single domain antibody (sdAb) conjugation, Creative Biolabs now offers sdAb-polystyrene beads labeling service for our customers all over the world. Based on our world-leading antibody engineering platform and years of extensive experience, we can not only provide high-efficiency common sdAb-polystyrene bead labeling services for our clients but also provide custom conjugation approach to meet our clients’ special research requirement.
Polystyrene itself is a thermoplastic material that exists in solid form at room temperature and melts when heated. Polystyrene beads is a kind of new functional polymeric materials in which nanoparticles as nuclear, polystyrene as the shell. In recent years, polystyrene beads have been increasing in biomedical applications. Because of its good adsorption properties, excellent optical mechanical properties, high surface activity, and recyclable characteristics, polystyrene beads have shown their unique advantages in clinical diagnosis, detection, immunoassay, cytology and other research fields.
The types of polystyrene beads:
Single domain antibodies (sdAbs), also known as domain bodies, are antibody fragment consisting of a single monomeric variable antibody domain, derived from the heavy-chain-only antibodies produced by camelids and sharks, or the specific developed human VH and VL domain. Compared with the conventional antibodies, sdAbs have a much smaller molecular weight which is only ~15 kDa. Due to a series of special characteristics, such as small size, simple production, and high affinity, sdAbs show great potential for the applications in biotechnical and therapeutic use.
Fig.1 Single Domain Antibody-Polystyrene beads labeling.
Now Creative Biolabs can combine single domain antibody service and polystyrene bead labeling service together to provide the sdAb-polystyrene beads labeling service. The coupling procedure relates to a primary amino group of a protein and a carbodiimide reaction of a carboxyl functional group bonded to the surface of the polystyrene beads. The carboxyl groups on the surface of the polystyrene beads must first be activated with a carbodiimide derivative prior to coupling the protein. Under the action of special chemical reagents (such as EDC), the covalent coupling of peptides, proteins, oligonucleotides and other biological ligands to the surface of microspheres is an important carrier for medical and molecular biology research.
With the extensive experience and advanced platform, Creative Biolabs is promising to have the capability to enable you to free up your time for core work and project. We are pleased to try our best to offer the best service and the most qualified products to satisfy each demand from our customers. If you are interested in our single domain antibody-polystyrene bead labeling service, please do not hesitate to inquire our experts for more details.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
