This product is a Ramos (RA 1) B cell engineering tool based on the Gold nanoparticles (N-acetyl-D-glucosamine, sialic acid/Wheat germ agglutinin) delivery system and CRISPR-based (SHS-317-sgRNA-NLS-Cas9-SCR7 pyrazine) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | DENV |
| Insert Clone | FT8 |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | sgRNA |
| Nuclease | NLS-Cas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | N-acetyl-D-glucosamine, sialic acid/Wheat germ agglutinin |
| Active Agents | Thymoquinone |
| Particle Size | 1-241 |
| Charge (mv) | 1 to -31 |
| Total Atom Count | -23000000 |
| Surface Atoms (%) | -4 |
| Specific Surface Area (m2/g) | -7 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Breast cancer; Lung cancer; Brain cancer; Colon cancer; Ovarian cancer |
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