This product is a Toledo B cell engineering tool based on the Liposomes (Anisamide/ Sigma receptors) delivery system and CRISPR-based (hROSA26-tracr RNA-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Toledo |
| Target | EMC8 |
| Insert Clone | BGJ-3607CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Mouse genome E-8 |
| Vehicles | Liposomes |
| Ligand/Receptor | Anisamide/ Sigma receptors |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | <500 |
| Charge (mv) | 6 to 86 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Liver cancer; Lung cancer; Colon cancer |
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