This product is a HS-Sultan B cell engineering tool based on the Dendrimers (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | HS-Sultan |
| Target | EphA2 |
| Insert Clone | A3H9CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Human genome |
| Vehicles | Dendrimers |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | Celastrol |
| Particle Size | 10-1000 |
| Charge (mv) | 10 to 35 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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