This product is a Raji-Luc2 B cell engineering tool based on the Micelles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (CCR5-SpCas9-NLS-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | EZR |
| Insert Clone | B6CR247 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-3 |
| Vehicles | Micelles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | Celastrol |
| Particle Size | 10-50 |
| Charge (mv) | -15 to -185 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
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