This product is a SU-DHL-8 B cell engineering tool based on the Quantum dots (Folate/ Folate Receptor) delivery system and CRISPR-based (hROSA26-crispr RNA-SpCas9-L755507) genome editor.
| Host Cell | SU-DHL-8 |
| Target | EZR |
| Insert Clone | EP886YCR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Quantum dots |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | <1660 |
| Charge (mv) | 3 to 20 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
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