This product is a RPMI 8226 B cell engineering tool based on the Gold nanoparticles (Fucoidan/P-selectin) delivery system and CRISPR-based (huROSA-26-sgRNA-Cpf1-L755507) genome editor.
| Host Cell | RPMI 8226 |
| Target | FLT1 |
| Insert Clone | BG-93E |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Fucoidan/P-selectin |
| Active Agents | ESC8 |
| Particle Size | <500 |
| Charge (mv) | -5 to -50 |
| Total Atom Count | -22,000,000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Breast cancer; Lung cancer; Colon cancer |
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