This product is a SKO-007 B cell engineering tool based on the Gold nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (huROSA-26-SpCas9-Cas9-Brefeldin A) genome editor.
| Host Cell | SKO-007 |
| Target | FLT1 |
| Insert Clone | BG-99E |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | SpCas9 |
| Nuclease | Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | Regorafenib |
| Particle Size | <2300 |
| Charge (mv) | 0 to -16 |
| Total Atom Count | -22,000,000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Breast cancer; Lung cancer; Colon cancer |
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