This product is a Raji-Luc2 B cell engineering tool based on the Nanoparticles (Hyaluronic acid/ RHAMM, CD44) delivery system and CRISPR-based (SHS-317-sgRNA-Cpf1-L755507) genome editor.
| Host Cell | Raji-Luc2 |
| Target | NAE1 |
| Insert Clone | BCGW-0341CR |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | L755507 |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Hyaluronic acid/ RHAMM, CD44 |
| Active Agents | Bortezomib |
| Particle Size | <1660 |
| Charge (mv) | <-1 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Breast cancer; Lung cancer; Liver cancer |
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