This product is a RPMI 1788 B cell engineering tool based on the Gold nanoparticles (Transferrin/Transferrin receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-Nocodazole) genome editor.
| Host Cell | RPMI 1788 |
| Target | NDUFB11 |
| Insert Clone | 8C5CR |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Transferrin/Transferrin receptor |
| Active Agents | Bortezomib |
| Particle Size | 10-50 |
| Charge (mv) | ≤50 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Breast cancer; Colorectal cancer; Ovarian cancer; Non-small-cell lung cancer; Liver cancer |
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