This product is a Raji-Luc2 B cell engineering tool based on the Magnetic nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-323-crRNA:tracrRNA duplex-Cas12-Brefeldin A) genome editor.
| Host Cell | Raji-Luc2 |
| Target | SNAI1 |
| Insert Clone | BCGS-3411CR |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Magnetic nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Regorafenib |
| Particle Size | 20-2850 |
| Charge (mv) | -1 to -20 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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