This product is a Ramos (RA 1) B cell engineering tool based on the Liposomes (EpCAM aptamer/Epithelial cell adhesion molecule) delivery system and CRISPR-based (SHS-227-huIgH296-Cas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | SNAI1 |
| Insert Clone | SN9H2CR |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | huIgH296 |
| Nuclease | Cas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-8 |
| Vehicles | Liposomes |
| Ligand/Receptor | EpCAM aptamer/Epithelial cell adhesion molecule |
| Active Agents | Thymoquinone |
| Particle Size | 10-1000 |
| Charge (mv) | 0 to -16 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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