This product is a Ramos (RA 1) B cell engineering tool based on the Nanoparticles (EGFR mAb/Epidermal Growth Factor Receptor) delivery system and CRISPR-based (hROSA26-crispr RNA-SpCas9-L755507) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | SNAI1 |
| Insert Clone | BCGS-6151CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Mouse genome E-7 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | EGFR mAb/Epidermal Growth Factor Receptor |
| Active Agents | DOX |
| Particle Size | 20-150 |
| Charge (mv) | < 0 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Pancreatic cancer |
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