This product is a Ramos (RA 1) B cell engineering tool based on the Solid lipid nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (SHS-227-tracr RNA-Cas9-Nocodazole) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | SPINT1 |
| Insert Clone | BCGS-0687CR |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-8 |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | ESC8 |
| Particle Size | 20-150 |
| Charge (mv) | <80 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Colorectal cancer; Breast cancer; Lung cancer; Liver cancer |
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