This product is a Raji-Luc2 B cell engineering tool based on the Nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (SHS-323-SpCas9-NLS-Cas9-L755507) genome editor.
| Host Cell | Raji-Luc2 |
| Target | SPINT1 |
| Insert Clone | BCGS-3752CR |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH responsive |
| Insertion sites | Human genome |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Regorafenib |
| Particle Size | <100 |
| Charge (mv) | 15-60 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colorectal cancer; Breast cancer; Lung cancer; Liver cancer |
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