This product is a Raji-Luc2 B cell engineering tool based on the Liposomes (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (SHS-323-crRNA:tracrRNA duplex-Cas12-Brefeldin A) genome editor.
| Host Cell | Raji-Luc2 |
| Target | SPINT1 |
| Insert Clone | BCGS-5101CR |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Liposomes |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | <1660 |
| Charge (mv) | 10-90 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | AAV |
| Vector Name | BCpCDH1 |
| Targeting Diseases | Colorectal cancer; Breast cancer; Lung cancer; Liver cancer |
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