This product is a Raji B cell engineering tool based on the Gold nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (SHS-229-huIgH296-Cpf1-Brefeldin A) genome editor.
| Host Cell | Raji |
| Target | αvβ5 Integrin |
| Insert Clone | BGB31 |
| Safe Harbor Sites (SHS) | SHS-229 |
| gRNA | huIgH296 |
| Nuclease | Cpf1 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | Thymoquinone |
| Particle Size | <500 |
| Charge (mv) | 6 to 92 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung cancer; Prostate cancer; Colorectal cancer |
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