This product is a Raji B cell engineering tool based on the Solid lipid nanoparticles (Transferrin/Transferrin receptor) delivery system and CRISPR-based (hROSA26-sgRNA-NLS-Cas9-L755507) genome editor.
| Host Cell | Raji |
| Target | αvβ5 Integrin |
| Insert Clone | BGB32 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | sgRNA |
| Nuclease | NLS-Cas9 |
| Enhancer | L755507 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Mouse genome E-8 |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Transferrin/Transferrin receptor |
| Active Agents | DOX |
| Particle Size | ≤24100 |
| Charge (mv) | 17-61 |
| Total Atom Count | -73000000 |
| Surface Atoms (%) | -0.6 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Lung cancer; Prostate cancer; Colorectal cancer |
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