Cas No.: 1644644-96-1
PRODUCT INFORMATION
Description
This is a heterobifunctional linker for bioorthogonal 'Click Chemistry.' It contains an amine-reactive N-hydroxysuccinimide (NHS) ester and a methyltetrazine moiety. The NHS ester is used to "install" the tetrazine handle onto a biomolecule (e.g., a protein or antibody) by reacting with its primary amines (lysines). The tetrazine group then participates in extremely fast, specific, and bioorthogonal Inverse-Electron-Demand Diels-Alder (IEDDA) "click" reactions with strained alkenes, such as trans-cyclooctene (TCO) or bicyclononyne (BCN), for cellular imaging or in vivo targeting.
Molecular Weight
327.30
Purity
>95.0%
Formula
C₁₅H₁₃N₅O₄
Product Type
Copper-Free Click Chemistry Reagents
Group 1
NHS
Group 2
Other
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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