m-PEG12-azide PEGylation Crosslinker (CAT#: OLY-1023-YS235)

Description

This is a monofunctional PEGylation reagent for 'Click Chemistry.' It features a long, 12-unit polyethylene glycol (PEG) chain that is capped with an inert methoxy (m) group at one end and a terminal azide at the other. The azide group is a bioorthogonal handle for copper-catalyzed (CuAAC) or copper-free (SPAAC) click reactions with alkyne- or cyclooctyne-functionalized molecules. It is used to attach a long, hydrophilic, and inert PEG spacer, which can improve solubility, reduce aggregation, and enhance the pharmacokinetic profile of biotherapeutics.

Molecular Weight

585.69

Purity

>98.0%

Formula

C₂₅H₅₁N₃O₁₂

Product Type

PEGylation Reagents

Group 1

Azide

Form (20 deg.C)

Liquid

Storage Condition

Store under inert gas, -20°C

Molecular Structure